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Details Generic Remeron (Mirtaz) Generic Name: Mirtazapine Strips of 10 x 15mg Tablets Manufactured by Sun Pharmaceuticals Use Generic Remeron (Mirtazapine) is prescribed for the treatment of major depression. Generic Remeron (Mirtazapine) is thought to work by adjusting the balance of the brain's natural chemical messengers, especially norepinephrine and serotonin. Dosage The recommended starting dose for Generic Remeron (Mirtazapine) is 15 mg/day, administered in a single dose, preferably in the evening prior to sleep. Patients not responding to the initial 15mg dose may benefit from dose increases up to a maximum of 45 mg/day. Check with your doctor to see your recommended dosage. Side Effects Side effects of Generic Remeron (Mirtazapine) cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Remeron. More common side effects may include: Abnormal dreams and thinking, constipation, dizziness, dry mouth, "flu-like" symptoms, increased appetite, sleepiness, weakness, weight gain. Less common side effects may include back pain, confusion, difficult or labored breathing, fluid retention, frequent urination, muscle pain, nausea, swelling of ankles or hands, tremors. Precautions Serious, sometimes fatal reactions have been known to occur when drugs such as Remeron are taken in combination with other drugs known as MAO inhibitors, including the antidepressants Nardil and Parnate. Never take Remeron with one of these drugs or within 14 days of discontinuing therapy with one of them; and allow at least 14 days between stopping Remeron and starting an MAO inhibitor. If you develop "flu-like" symptoms, a sore throat, chills or fever, mouth sores, or any other signs of infection, call your doctor; these symptoms may signal a serious underlying condition. Remeron tends to raise cholesterol levels in some people. If you have a cholesterol problem, be sure to mention it to your doctor before starting therapy with Remeron. Remeron should be used with caution if you have active liver or kidney disease, or heart or blood pressure problems. Also be sure to tell your doctor if you have a history of seizures, mania (extremely high spirits), hypomania (mild excitability), drug use, or any other physical or emotional problems. While first taking this medication you may feel dizzy or light-headed, especially when getting up from a lying or sitting position. If getting up slowly doesn't help, or if this problem continues, notify your doctor. If you must avoid phenylalanine, do not use the SolTab form of Remeron, which contains this substance. Possible food and drug interactions when taking this medication. Never combine Remeron with an MAO inhibitor; and do not drink alcohol while taking this medication. If Remeron is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Remeron with tranquilizers such as Valium, Xanax, and Ativan.