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Contact us for availability Details Product Name: Combivir Drug Name: Lamivudine/Zidovudine Packaging Type: Packets of 60 x 150/300 mg Tablets Manufacturer: GlaxoSmithKline Use: Combivir belongs to a class of anti-HIV drugs called Nucleoside Reverse Transcriptase Inhibitors (NRTIs). The active ingredients inhibit the reproduction of HIV in the body. They are used together to treat HIV which causes AIDS. However, this medication is NOT a cure. How to take it: Take lamivudine and zidovudine exactly as directed by your doctor. Take each dose with a full glass of water. Lamivudine and zidovudine can be taken with or without food. Lamivudine and zidovudine is usually taken twice a day. Follow your doctor's instructions. Side effects: If you experience any of the following serious side effects, stop taking lamivudine and zidovudine and seek emergency medical attention or notify your doctor immediately; an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); muscle pain or weakness; or peripheral neuropathy (nerve damage), which may cause numbness, tingling, or pain. Other, less serious side effects may be more likely to occur. Continue taking lamivudine and zidovudine and talk to your doctor if you experience mild nausea, vomiting, diarrhea, or decreased appetite; a headache; dizziness; insomnia; or redistribution of body fat (loss of fat from the arms, legs, and face and increased fat around the neck, breast, and trunk). Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. Precautions: Serious blood problems including low levels of red and/or white blood cells have occurred with the use of zidovudine. Contact your doctor immediately if you develop unusual fatigue, pale skin, sore throat, fever, or chills which may be signs of blood problems. Lactic acidosis and severe liver problems, including fatal cases, have been reported with the use of lamivudine and zidovudine, alone or in combination. Contact your doctor immediately if you experience nausea, vomiting, or unusual or unexpected stomach discomfort; weakness and tiredness; shortness of breath; weakness in the arms and legs; yellowing of the skin or eyes; or pain in the upper stomach area. These may be early symptoms of lactic acidosis or liver problems. Serious, even fatal, cases of pancreatitis (inflammation of the pancreas) have been reported with the use of some reverse transcriptase inhibitors. Notify your doctor immediately if you develop symptoms of pancreatitis including nausea, vomiting, diarrhea, abdominal pain, and/or fever. Avoid alcohol while taking lamivudine and zidovudine. Alcohol may increase the risk of damage to the pancreas and/or liver. Follow your doctor's instructions with respect to high-risk activities such as unprotected sex and the sharing of needles. Lamivudine and zidovudine is not a cure for HIV or AIDS, and you can still transmit the virus to others during therapy with this medication.